GRIP1 anticorps (C-Term)

N° du produit ABIN6991819

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIP1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GRIP1 anticorps (C-Term) (ABIN6991819)

Antigène: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GRIP1 anticorps

Épitope: C-Term

Purification: GRIP1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1. The immunogen is located within the last 50 amino acids of GRIP1.

Isotype: IgG

Information d'application

Indications d'application: GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GRIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GRIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GRIP1

Antigène: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Autre désignation: GRIP1

Sujet: GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).

Poids moléculaire: Predicted: 118 kDa

Observed: 115 kDa

ID gène: 23426

NCBI Accession: NP_066973

UniProt: Q9Y3R0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway